Vcam1 Mouse Monoclonal Antibody [Clone ID: eBioMR106 (MR106)]
CAT#: TA320510
Mouse Anti-Rat CD106 (VCAM-1) Purified (50 ug)
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CNY 1,960.00
CNY 300.00
CNY 1,430.00
CNY 7,106.00
Specifications
Product Data | |
Clone Name | eBioMR106 (MR106) |
Applications | FC |
Recommend Dilution | Flow, IHC, IP, WB |
Reactivity | Rat |
Host | Mouse |
Clonality | Monoclonal |
Formulation | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | vascular cell adhesion molecule 1 |
Database Link | |
Background | The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response. |
Synonyms | CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561 |
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