Aromatase (CYP19A1) Rabbit Polyclonal Antibody

CAT#: TA321053

Anti-ARO Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Cited in 1 publication.

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经常一起买 (4)
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Purified recombinant protein of Human cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293 cells, 20 µg
    • 20 ug

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Purified recombinant protein of Human cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1), transcript variant 1, full length, with C-terminal MYC/DDK tag, expressed in HEK293 cells, 100 µg
    • 100 ug

CNY 9,998.00

Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 10-50
Positive control: Human esophagus cancer
Predicted cell location: Cell membrane
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 240-255 amino acids of Human Aromatase
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 58 kDa
Gene Name cytochrome P450 family 19 subfamily A member 1
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis; three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
Synonyms ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Reference Data
Protein Families Druggable Genome, P450
Protein Pathways Androgen and estrogen metabolism, Metabolic pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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