BDKRB2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: HUVEC cell lysate IHC: 25-50 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 377-391 amino acids of human bradykinin receptor B2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45 kDa
Gene Name	bradykinin receptor B2
Database Link	NP_000614 Entrez Gene 12062 MouseEntrez Gene 25245 RatEntrez Gene 624 Human UniProt ID P30411
Background	This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation; edema; smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
Synonyms	B2R; BK-2; BK2; BKR2; BRB2
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton

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