Orexin Receptor 2 (HCRTR2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 405-419 amino acids of human hypocretin (orexin) receptor 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	hypocretin receptor 2
Database Link	NP_001517 Entrez Gene 25605 RatEntrez Gene 387285 MouseEntrez Gene 3062 Human UniProt ID O43614
Background	The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A.
Synonyms	OX2R
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Neuroactive ligand-receptor interaction

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