IL13 receptor alpha 1 (IL13RA1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Mouse heart tissue, 293T cell lysates IHC: 100-200 Positive control: Human esophagus cancer Predicted cell location: Cell membrane
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 25-363 amino acids of Human Interleukin 13 receptor, alpha 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	interleukin 13 receptor subunit alpha 1
Database Link	NP_001551 Entrez Gene 16164 MouseEntrez Gene 3597 Human UniProt ID P78552
Background	The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha; a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor; and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2; and thus may mediate the signaling processes that lead to the activation of JAK1; STAT3 and STAT6 induced by IL13 and IL4.
Synonyms	CD213A1; CT19; IL-13Ra; NR4
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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