ARF6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela and 293T cells, mouse liver tissue, A431 and MCF-7 cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 162-175 amino acids of Human ADP-ribosylation factor 6
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20 kDa
Gene Name	ADP ribosylation factor 6
Database Link	NP_001654 Entrez Gene 11845 MouseEntrez Gene 79121 RatEntrez Gene 382 Human UniProt ID P62330
Background	This gene encodes a member of the human ARF gene family; which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane; and regulates vesicular trafficking; remodelling of membrane lipids; and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
Synonyms	DKFZp564M0264
Reference Data
Protein Pathways	Endocytosis, Fc gamma R-mediated phagocytosis

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