EDG4 (LPAR2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 340-351 amino acids of human lysophosphatidic acid receptor 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	lysophosphatidic acid receptor 2
Database Link	NP_004711 Entrez Gene 53978 MouseEntrez Gene 9170 Human UniProt ID Q9HBW0
Background	This gene encodes a member of family I of the G protein-coupled receptors; as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization; a critical cellular response to LPA in cells; through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined.
Synonyms	EDG-4; EDG4; LPA-2; LPA2
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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