GDF15 Rabbit Polyclonal Antibody
CAT#: TA321674S
Anti-GDF15 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 150-300 Positive control: Human liver cancer Predicted cell location: Secreted |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 195-308 amino acids of human growth differentiation factor 15 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | growth differentiation factor 15 |
Database Link | |
Background | Bone morphogenetic proteins (e.g.; BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF15 mRNA is most abundant in the liver; with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver; kidney; heart and lung. |
Synonyms | GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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