GPR6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: Human cerebrum tissue lysate
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 347-362 amino acids of Human G protein-coupled receptor 6
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	38 kDa
Gene Name	G protein-coupled receptor 6
Database Link	NP_005275 Entrez Gene 83683 RatEntrez Gene 140741 MouseEntrez Gene 2830 Human UniProt ID P46095
Background	G protein-coupled receptor 6; also known as?GPR6; is a?protein?which in humans is encoded by the?GPR6gene. GPR6 is a member of the G protein-coupled receptor family of transmembrane receptors. It has been reported that GPR6 is both constitutively active but in addition is further activated by sphingosine-1-phosphate. GPR6 up-regulates cyclic AMP levels and promotes neurite outgrowth.
Synonyms	G protein-coupled receptor 6
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane

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