YES1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1000-5000 WB positive control: Lncap cells
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 10-193 amino acids of human v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	61 kDa
Gene Name	YES proto-oncogene 1, Src family tyrosine kinase
Database Link	NP_005424 Entrez Gene 22612 MouseEntrez Gene 24884 RatEntrez Gene 7525 Human UniProt ID P07947
Background	This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18; and a corresponding pseudogene has been found on chromosome 22.
Synonyms	c-yes; HsT441; P61-YES; Yes
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Adherens junction, Tight junction

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