TRAF7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Jurkat cells IHC: 15-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 44-57 amino acids of human TNF receptor-associated factor 7, E3 ubiquitin protein ligase
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	67 kDa
Gene Name	TNF receptor associated factor 7
Database Link	NP_115647 Entrez Gene 84231 Human UniProt ID Q6Q0C0
Background	Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors; such as TRAF7; are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family; the TRAF domain; which is involved in self-association and receptor binding.
Synonyms	RFWD1; RNF119
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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