Aquaporin 1 (AQP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Cell membrane
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 255-269 amino acids of Human aquaporin 1 (Colton blood group)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	aquaporin 1 (Colton blood group)
Database Link	NP_000376 Entrez Gene 11826 MouseEntrez Gene 25240 RatEntrez Gene 358 Human UniProt ID P29972
Background	Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms	28-kDa; 28kDa; AQP-CHIP; aquaporin 1; aquaporin 1 (channel-forming integral protein; aquaporin 1 (Colton blood group); channel-like integral membrane protein; CHIP28; CO; CO blood group); Colton blood group; MGC26324
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane

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