MUC16 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human thyroid cancer Predicted cell location: cytoplasm, Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from c-terminal 13 amino acids of Human Mucin 16, cell surface associated
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	mucin 16, cell surface associated
Database Link	NP_078966 Entrez Gene 94025 Human UniProt ID Q8WXI7
Background	CA-125?(cancer?antigen?125 or carbohydrate antigen 125) also known as?mucin 16?or?MUC16?is a?protein?that in humans is encoded by the?MUC16?gene. MUC16 is a member of the mucin family glycoproteins. CA-125 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers;or other benign conditions. Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas.
Synonyms	CA125
Reference Data

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