Persephin receptor (GFRA4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: 231 cell lysate IHC: 50-100 Positive control: Human liver cancer Predicted cell location: Secreted
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 266-279 amino acids of human GDNF family receptor alpha 4
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	GDNF family receptor alpha 4
Database Link	NP_071422 Entrez Gene 64096 Human UniProt ID Q9GZZ7
Background	The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin; and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms	GDNF family receptor alpha 4; GFR receptor alpha 4; OTTHUMP00000030106; OTTHUMP00000030107; persephin receptor
Reference Data
Protein Families	Druggable Genome

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