DAP13 (NDUFA12) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm, Cell membrane
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 40-53 amino acids of Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NADH:ubiquinone oxidoreductase subunit A12
Database Link	NP_061326 Entrez Gene 66414 MouseEntrez Gene 55967 Human UniProt ID Q9UI09
Background	This gene encodes a protein which is part of mitochondrial complex 1; part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
Synonyms	B17.2; DAP13
Reference Data

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