LRIG1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human lung cancer Predicted cell location: Cytoplasm, Cell membrane
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 1073-1085 amino acids of Human leucine-rich repeats and immunoglobulin-like domains 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	leucine-rich repeats and immunoglobulin like domains 1
Database Link	NP_056356 Entrez Gene 26018 Human UniProt ID Q96JA1
Background	Leucine-rich repeats and immunoglobulin-like domains protein 1?is a?protein?that in humans is encoded by the?LRIG1?gene.?It encodes a?transmembrane protein?that has been shown to interact with receptor tyrosine kinases of the?EGFR-family?;?MET?and?RET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases; through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Synonyms	LIG-1; LIG1
Reference Data
Protein Families	Transmembrane

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