GADD45G Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 100-200 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	growth arrest and DNA damage inducible gamma
Database Link	NP_006696 Entrez Gene 23882 MouseEntrez Gene 291005 RatEntrez Gene 10912 Human UniProt ID O95257
Background	This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Synonyms	CR6; DDIT2; GADD45gamma; GRP17
Reference Data
Protein Pathways	Cell cycle, MAPK signaling pathway, p53 signaling pathway

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