MAP4K5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 506-819 amino acids of human mitogen-activated protein kinase kinase kinase kinase?
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	mitogen-activated protein kinase kinase kinase kinase 5
Database Link	NP_006566 Entrez Gene 399510 MouseEntrez Gene 11183 Human UniProt ID Q9Y4K4
Background	This gene encodes a member of the serine/threonine protein kinase family; that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells; which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.?
Synonyms	GCKR; KHS; KHS1; MAPKKKK5
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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