KCNC1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse liver tissue IHC: 25-100 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm, Cell membrane
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide peptide corresponding to a region derived from 499-511 amino acids of human potassium voltage-gated channel, Shaw-related subfamily, member 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	58 kDa
Gene Name	potassium voltage-gated channel subfamily C member 1
Database Link	NP_004967 Entrez Gene 16502 MouseEntrez Gene 3746 Human UniProt ID P48547
Background	The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity; this gene is similar to one of these subfamilies; namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Multiple transcript variants encoding different isoforms have been inferred for this gene based on orthologous loci.
Synonyms	EPM7; KV3.1; KV4; NGK2
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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