ABCG1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: HT-29 cells IHC: 25-100 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 349-362 amino acids of human ATP-binding cassette, sub-family G (WHITE), member 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	76 kDa
Gene Name	ATP binding cassette subfamily G member 1
Database Link	NP_004906 Entrez Gene 9619 Human UniProt ID P45844
Background	The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport; and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
Synonyms	ABC8; WHITE1
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ABC transporters

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