AKAP6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 2249-2262 amino acids of human A kinase (PRKA) anchor protein 6
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	A-kinase anchoring protein 6
Database Link	NP_004265 Entrez Gene 9472 Human UniProt ID Q13023
Background	The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins; which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane; and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum.
Synonyms	ADAP6; ADAP100; AKAP100; mAKAP; PRKA6
Reference Data
Protein Families	Druggable Genome

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