COX8A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 10-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cytochrome c oxidase subunit 8A
Database Link	NP_004065 Entrez Gene 1351 Human UniProt ID P10176
Background	The protein encoded by this gene is the terminal enzyme of the respiratory chain; coupling the transfer of electrons from cytochrome c to molecular oxygen; with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits; which perform the catalytic function; the eukaryotic enzyme contains nuclear-encoded smaller subunits; ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits.
Synonyms	COX; COX8; COX8-2; COX8L; VIII; VIII-L
Reference Data
Protein Families	Transmembrane
Protein Pathways	Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

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