TXN Rabbit Polyclonal Antibody
CAT#: TA322865S
Anti-TXN Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
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CNY 1,430.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 1000-5000 WB positive control: Hela and MCF7 cells, human liver cancer tissue IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm, Nucleus |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 90-105 amino acids of human thioredoxin |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 12 kDa |
Gene Name | thioredoxin |
Database Link | |
Background | The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins; which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins; and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO); and thereby inhibits caspase-3 activity. |
Synonyms | TRDX; TRX; TRX1 |
Reference Data | |
Protein Families | Druggable Genome |
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