GRP94 (HSP90B1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela cells and human liver cancer tissue, Jurkat and NIH/3T3 cells IHC: 50-200 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to N terminal 315 amino acids of human heat shock protein 90kDa beta (Grp94), member 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	92 kDa
Gene Name	heat shock protein 90kDa beta family member 1
Database Link	NP_003290 Entrez Gene 22027 MouseEntrez Gene 362862 RatEntrez Gene 7184 Human UniProt ID P14625
Background	This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states; including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
Synonyms	ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer

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