SLC1A4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human liver cancer tissue IHC: 25-100 Positive control: Human cervical cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 520-532 amino acids of Human solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56 kDa
Gene Name	solute carrier family 1 member 4
Database Link	NP_003029 Entrez Gene 55963 MouseEntrez Gene 6509 Human UniProt ID P43007
Background	Neutral amino acid transporter A?is a?protein?that in humans is encoded by the?SLC1A4?gene. In melanocytic cells SLC1A4 gene expression may be regulated by?MITF. ASCT1 does not transport glutamate or aspartate but alanine; serine; cysteine; and threonine instead. ASCT1 transporter functions primarily as an amino acid exchanger. Transport is associated with a chloride channel activity that is thermodynamically uncoupled from amino acid transport.
Synonyms	ASCT1; SATT; SPATCCM
Reference Data
Protein Families	Druggable Genome, Transmembrane

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