NME3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse kidney tissue
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	19 kDa
Gene Name	NME/NM23 nucleoside diphosphate kinase 3
Database Link	NP_002504 Entrez Gene 79059 MouseEntrez Gene 4832 Human UniProt ID Q13232
Background	Nucleoside diphosphate kinase 3 is an enzyme that in humans is encoded by the NME3 gene. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism; using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Synonyms	c371H6.2; DR-nm23; NDPK-C; NDPKC; NM23-H3; NM23H3
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Purine metabolism, Pyrimidine metabolism

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