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Cathepsin B (CTSB) Rabbit Polyclonal Antibody
CAT＃: TA323091S
Anti-CTSB Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 80-333 amino acids of human cathepsin B |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | cathepsin B |
| Database Link | |
| Background | The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains; both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease; the most common cause of dementia. Overexpression of the encoded protein; which is a member of the peptidase C1 family; has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. |
| Synonyms | APPS; CPSB |
| Reference Data | |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Antigen processing and presentation, Lysosome |
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