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ID4 Rabbit Polyclonal Antibody
CAT＃: TA323154S
Anti-ID4 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
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Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 20-100 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 19-38 amino acids of Human inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | inhibitor of DNA binding 4, HLH protein |
| Database Link | |
| Background | DNA-binding protein inhibitor ID-4?is a?protein?that in humans is encoded by the?ID4?gene. Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative (antimorph) HLH proteins encoded by Id-related genes; such as ID4; also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently; Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins . |
| Synonyms | bHLHb27; IDB4 |
| Reference Data | |
| Protein Families | ES Cell Differentiation/IPS, Transcription Factors |
| Protein Pathways | TGF-beta signaling pathway |
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