PSD95 (DLG4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 93-106 amino acids of Human discs, large homolog 4 (Drosophila)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	discs large MAGUK scaffold protein 4
Database Link	NP_001356 Entrez Gene 13385 MouseEntrez Gene 29495 RatEntrez Gene 1742 Human UniProt ID P78352
Background	This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein; DLG2; and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors; ion channels; and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	PSD95; SAP-90; SAP90
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Huntington's disease

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