NeuN (RBFOX3) Rabbit Polyclonal Antibody

CAT#: TA323300S

Anti-RBFOX3 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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经常一起买 (2)
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Transient overexpression lysate of hexaribonucleotide binding protein 3 (HRNBP3)
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: Mouse brain tissue lysate
IHC: 50-200
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm and Nucleus
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 88-102 amino acids of RNA binding protein, fox-1 homolog (C. elegans) 3
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 34 kDa
Gene Name RNA binding protein, fox-1 homolog 3
Background Immunoprecipitation and mass spectrometry of the two major NeuN species at 45–50 kDa identified both as the RNA binding protein Rbfox3 (a member of the Fox family of alternative splicing factors); confirming and extending the identification of the 45 kDa band as Rbfox3. Mapping of the anti-NeuN reactive epitopes in both R3hdm2 and Rbfox3 reveals a common proline- and glutamine-rich domain that lies at the N-terminus of the Rbfox3 protein. Nuclear Rbfox3 isoforms can also enhance the inclusion of cryptic exons in the Rbfox2 mRNA; resulting in nonsense-mediated decay of the message; thereby contributing to the negative regulation of Rbfox2 by Rbfox3 through a novel mechanism.
Synonyms FOX-3; FOX3; HRNBP3; NEUN
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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