NQO1 Rabbit Polyclonal Antibody
CAT#: TA323406S
Anti-NQO1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 1,280.00
CNY 300.00
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CNY 2,900.00
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 500-2000 WB positive control: Hela cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 260-274 amino acids of Human NAD(P)H dehydrogenase, quinone 1 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 27 kDa |
Gene Name | NAD(P)H quinone dehydrogenase 1 |
Database Link | |
Background | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD); an increased risk of hematotoxicity after exposure to benzene; and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants; encoding different isoforms; have been characterized. |
Synonyms | DHQU; DIA4; DTD; NMOR1; NMORI; QR1 |
Reference Data | |
Protein Families | Druggable Genome |
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