MAGED1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Human fetal brain tissue IHC: 25-100 Positive control: Human tonsil Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 300 amino acids of human melanoma antigen family D, 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	86 kDa
Gene Name	MAGE family member D1
Database Link	NP_001005332 Entrez Gene 84469 RatEntrez Gene 94275 MouseEntrez Gene 9500 Human UniProt ID Q9Y5V3
Background	This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms	DLXIN-1; NRAGE
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Neurotrophin signaling pathway

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