NPY2R Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 15-50 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 367-381 amino acids of human neuropeptide Y receptor Y2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	neuropeptide Y receptor Y2
Database Link	NP_000901 Entrez Gene 18167 MouseEntrez Gene 4887 Human UniProt ID P49146
Background	Neuropeptide Y receptor type 2 (Y2R)?is a?protein?that in humans is encoded by the?NPY2R?gene. Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31; Gln-34] PP > [Leu-31; Pro-34] NPY > PP; [Pro-34] PYY and NPY free acid. High levels in amygdala; corpus callosum; hippocampus and subthalamic nucleus. Also detectable in caudate nucleus; hypothalamus and substantia nigra.
Synonyms	NPY2-R
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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