Luteinizing Hormone beta (LHB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse adrenal gland tissue IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Secreted
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 114-128 amino acids of Human luteinizing hormone beta polypeptide
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	15 kDa
Gene Name	luteinizing hormone beta polypeptide
Database Link	NP_000885 Entrez Gene 16866 MouseEntrez Gene 3972 Human UniProt ID P01229
Background	This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.?
Synonyms	CGB4; HH23; LSH-B; LSH-beta
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	GnRH signaling pathway, Neuroactive ligand-receptor interaction

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