NMDAR1 (GRIN1) Rabbit Polyclonal Antibody
CAT#: TA323549S
Anti-GRIN1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 35-49 amino acids of human glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | glutamate ionotropic receptor NMDA type subunit 1 |
Database Link | |
Background | The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors; members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses; which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms; possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. |
Synonyms | GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1 |
Reference Data | |
Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction |
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