beta 2 Adrenergic Receptor (ADRB2) Rabbit Polyclonal Antibody
CAT#: TA323758
Anti-ADRB2 Rabbit Polyclonal Antibody
Size: 25 ul
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CNY 1,999.00
CNY 3,280.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 1000-2000 WB positive control: Hela and A549 cells IHC: 15-50 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 21-33 amino acids of Human adrenoceptor beta 2, surface |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 46 kDa |
Gene Name | adrenoceptor beta 2 |
Database Link | |
Background | This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors; the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein; an adenylyl cyclase; cAMP-dependent kinase; and the counterbalancing phosphatase; PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms; point mutations; and/or downregulation of this gene are associated with nocturnal asthma; obesity and type 2 diabetes.? |
Synonyms | ADRB2R; ADRBR; B2AR; BAR; BETA2AR |
Reference Data | |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Calcium signaling pathway, Endocytosis, Neuroactive ligand-receptor interaction |
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