TRAF3IP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human brain malignant glioma tissue IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from C terminal 250 amino acids of human TNF receptor-associated factor 3 interacting protein 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	79 kDa
Gene Name	TRAF3 interacting protein 1
Database Link	NP_001132962 Entrez Gene 74019 MouseEntrez Gene 363286 RatEntrez Gene 26146 Human UniProt ID Q8TDR0
Background	This protein plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. It can interacts with IL13RA1 and binds to microtubules, TRAF3 and DISC1.
Synonyms	IFT54; MIP-T3; MIPT3; SLSN9
Reference Data
Protein Families	Druggable Genome

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