DISC1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 737-750 amino acids of Human disrupted in schizophrenia 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	disrupted in schizophrenia 1
Database Link	NP_061132 Entrez Gene 27185 Human UniProt ID Q9NRI5
Background	This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus; cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
Synonyms	C1orf136; SCZD9
Reference Data

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