GSK3 beta (GSK3B) Rabbit Polyclonal Antibody

CAT#: TA323991

Anti-GSK3B (Phospho-Tyr216) Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 3,800.00


货期*
2周

规格
    • 100 ul

Product images

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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: A549 and Hela cell lysates
IHC: 20-100
Positive control: Human tonsil
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Modifications Phospho-specific
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of tyrosine 216 (V-S-Y(p)-I-C) derived from Human GSK3β.
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 47 kDa
Gene Name glycogen synthase kinase 3 beta
Background Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin.
Synonyms glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Alzheimer's disease, Axon guidance, Basal cell carcinoma, B cell receptor signaling pathway, Cell cycle, Chemokine signaling pathway, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Hedgehog signaling pathway, Insulin signaling pathway, Melanogenesis, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, T cell receptor signaling pathway, Wnt signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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