United States
Germany
Japan
United Kingdom
China
ALS2CR2 (STRADB) Rabbit Polyclonal Antibody
CAT＃: TA324160S
Anti-STRADB rabbit polyclonal antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
CNY 1,280.00
Product images
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Mouse pancreas and spleen tissue, mouse heart tissue and 293T cells IHC: 25-100 Positive control: Human lymphoma Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 139-378 amino acids of human STE20-related kinase adaptor beta |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | STE20-related kinase adaptor beta |
| Database Link | |
| Background | This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | ALS2CR2; CALS-21; ILPIP; ILPIPA; PAPK; PRO1038 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
| 抗体相关资料 |
其它ALS2CR2产品
