Synaptotagmin VII (SYT7) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Lncap and SKOV3 cells IHC: 15-50 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 54-200 amino acids of human synaptotagmin VII
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46 kDa
Gene Name	synaptotagmin 7
Database Link	NP_001238994 Entrez Gene 54525 MouseEntrez Gene 9066 Human UniProt ID O43581
Background	This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms	IPCA-7; IPCA7; PCANAP7; SYT-VII; SYTVII
Reference Data
Protein Families	Secreted Protein, Transmembrane

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