SPDEF Rabbit Polyclonal Antibody
CAT#: TA324209S
Anti-SPDEF Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 2,900.00
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Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-100 Positive control: Human colorectal cancer Predicted cell location: Nucleus |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 129-332 amino acids of human SAM pointed domain containing ets transcription factor |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | SAM pointed domain containing ETS transcription factor |
Database Link | |
Background | The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells; and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain; breast; lung and ovarian tumors; compared to the corresponding normal tissues; and it shows better tumor-association than other cancer-associated molecules; making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Synonyms | bA375E1.3; PDEF |
Reference Data | |
Protein Families | Transcription Factors |
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