OASL Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 207 amino acids of human 2'-5'-oligoadenylate synthetase-like
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	2'-5'-oligoadenylate synthetase like
Database Link	NP_937856 Entrez Gene 8638 Human UniProt ID Q15646
Background	OASL encodes an interferon-induced protein that is a member of the 2-5A synthetase family. 2-prime;5-prime oligoadenylates (2-5As) bind to and activate RNase L; resulting in general RNA degradation and consequent inhibition of protein synthesis. 2-5As are produced by a well-conserved family of interferon-induced enzymes; the 2-5A synthetases or OASs
Synonyms	OASLd; p59 OASL; p59-OASL; p59OASL; TRIP-14; TRIP14
Reference Data
Protein Families	Druggable Genome

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