IRS1 Rabbit Polyclonal Antibody
CAT#: TA325573
Rabbit Polyclonal IRS-1 (Ser307) Antibody (Phospho-specific)
Size: 30 ul
Need it in bulk or conjugated?
Get a free quote
CNY 1,999.00
CNY 3,280.00
Cited in 2 publications. |
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500 |
Reactivity | Human, Mouse, Rat |
Modifications | Phospho-specific |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against A synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine 307 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 180 kDa |
Gene Name | insulin receptor substrate 1 |
Database Link | |
Background | IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2. |
Synonyms | HIRS-1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
Ursolic acid ameliorates adipose tissue insulin resistance in aged rats via activating the Akt-glucose transporter 4 signaling pathway and inhibiting inflammation
,null,
Experimental and Therapeutic Medicine
,PubMed ID 34737806
[IRS1]
|
6-Gingerol Improves Ectopic Lipid Accumulation, Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle of ageing Rats: Dual Stimulation of the AMPK/PGC-1α Signalling Pathway via Plasma Adiponectin and Muscular AdipoR1
,Liu, L;Yao, L;Wang, S;Chen, Z;Han, T;Ma, P;Jiang, L;Yuan, C;Li, J;Ke, D;Li, C;Yamahara, J;Li, Y;Wang, J;,
Mol Nutr Food Res
,PubMed ID 30575271
[IRS1]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |