MEK4 (MAP2K4) Rabbit Polyclonal Antibody

CAT#: TA325643

Rabbit Polyclonal SEK1/MKK4 (Thr261) Antibody (Phospho-specific)



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Product images

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity Human, Mouse, Rat
Modifications Phospho-specific
Host Rabbit
Clonality Polyclonal
Immunogen The antiserum was produced against A synthesized peptide derived from human SEK1/MKK4 around the phosphorylation site of Threonine 261
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration lot specific
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 44 kDa
Gene Name mitogen-activated protein kinase kinase 4
Background MKK4 dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38 but not ERK1 or -2. Mediates cellular responses to various cellular stresses and inflammatory cytokines. Phosphorylation by Akt inhibits MKK4 and suppresses stress-activated signal transduction.
Synonyms JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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