MTOR Rabbit Polyclonal Antibody

CAT#: TA325698

Rabbit Polyclonal mTOR (Ser2481) Antibody (Phospho-specific)



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Product images

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Recombinant protein of human FK506 binding protein 12-rapamycin associated protein 1 (FRAP1/MTOR), 100 µg
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500
Reactivity Human, Mouse, Rat
Modifications Phospho-specific
Host Rabbit
Clonality Polyclonal
Immunogen The antiserum was produced against A synthesized peptide derived from human mTOR around the phosphorylation site of Serine 2481
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration lot specific
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 288 kDa
Gene Name mechanistic target of rapamycin
Background an atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Synonyms FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Acute myeloid leukemia, Adipocytokine signaling pathway, ErbB signaling pathway, Glioma, Insulin signaling pathway, mTOR signaling pathway, Pathways in cancer, Prostate cancer, Type II diabetes mellitus
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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