TrkB (NTRK2) Rabbit Polyclonal Antibody
CAT#: TA325758
Rabbit Polyclonal Trk B (Tyr515) Antibody (Phospho-specific)
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CNY 1,999.00
CNY 3,280.00
Cited in 1 publication. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
CNY 9,998.00
CNY 3,080.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200 |
Reactivity | Human, Mouse, Rat |
Modifications | Phospho-specific |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against A synthesized peptide derived from human Trk B around the phosphorylation site of Tyrosine 515 (peptide seq 509-521aa: VIENPQY(p)FGITN) |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 145 kDa |
Gene Name | neurotrophic receptor tyrosine kinase 2 |
Database Link | |
Background | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. |
Synonyms | GP145-TrkB; trk-B; TRKB |
Note | The amino acid position may vary depending on the source of reference sequence: position 516 base on NP_001018074.1, position 532 base on NP_006171.2. |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | MAPK signaling pathway, Neurotrophin signaling pathway |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Obestatin prevents H2O2-induced damage through activation of TrkB in RGC-5 cells
,Liu, Y;Xing, YX;Gao, XY;Kuang, HY;Zhang, ;liu, R;,
Biomedicine & Pharmacotherapy
,PubMed ID 29136785
[NTRK2]
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