Tuberin (TSC2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human Tuberin/TSC2
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	200 kDa
Gene Name	tuberous sclerosis 2
Database Link	NP_000539 Entrez Gene 22084 MouseEntrez Gene 24855 RatEntrez Gene 7249 Human UniProt ID P49815
Background	Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin.
Synonyms	LAM; PPP1R160; TSC4
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Insulin signaling pathway, mTOR signaling pathway, p53 signaling pathway

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