WNK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human WNK1 around the phosphorylation site of Threonine 58
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	230 kDa
Gene Name	WNK lysine deficient protein kinase 1
Database Link	NP_001171914 Entrez Gene 116477 RatEntrez Gene 232341 MouseEntrez Gene 65125 Human UniProt ID Q9H4A3
Background	WNK1 a serine-threonine protein kinase that controls sodium and chloride ion transport. May regulate the activity of the thiazide-sensitive Na-Cl cotransporter SLC12A3 by phosphorylation. May also play a role in actin cytoskeletal reorganization.
Synonyms	HSAN2; HSN2; KDP; p65; PPP1R167; PRKWNK1; PSK
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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