WAVE 1 (WASF1) Mouse Monoclonal Antibody [Clone ID: S91-36]
CNY 5,830.00
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CNY 3,080.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | S91-36 |
Recommend Dilution | WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Synthetic peptide amino acids 477-498 of human Wave1/Wasp family1 |
Formulation | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
Concentration | lot specific |
Purification | Protein G Purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | WAS protein family member 1 |
Database Link | |
Background | The Wiskott-Aldrich syndrome protein (WASP) family plays essential roles in the regulation of actin polymerization. There are five WASP family members: Wasp, N-WASP, Wave1 (WASP family verprolin-homologous protein 1), WAVE2 and WAVE3. The Wasp family proteins share a conserved C-terminal region called the verprolin homology, cofilin homology and acidic domain . The Wave/Scar family of prtoteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterized as major regulators of lamellipodia formation downstream of Rac activation, and as members of large protein complexes. IT has been found that all three Scar/Wave isoforms behave similarily and are likely to participate in the same kinds of protein complexes . |
Synonyms | SCAR1; WAVE; WAVE1 |
Note | Detects ~75kDa. |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Adherens junction, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton |
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